Mice Have Pathway Makes Cancer Reoccurs

Cancer is a very dangerous disease that humans work hard to handle and treat. This disease affects a large number of humans worldwide and is rarely treated. Different forms of cancer have different treatments and all treatments are considered basic and not well developed. The problem with cancer is the high chances of it occurring again in the patient.

A new study conducted by a team of scientists from the Duke Cancer Institute were focusing on studying cancer in mice, trying to find solution for the disease. During the study a new discovery was made that showed a new pathway in mice that might be the cause of breast cancer recurring.

The study was led and written by PhD holder, James V. Alvarez who is an assistant professor in Duke’s Department of Pharmacology & Cancer Biology together with Andrea Walens. They published the study and the results in the journal of eLife which is an online journal.

They commented on their findings saying, “These are the cells that are left over the following therapy, and we haven’t known much about them because we can’t see them. There are too few of them to show up in mammography or PET scans. But using mouse models that replicate recurrent HER2-positive breast cancers, which afflict about 20 percent of women, we were able to locate the residual cancer cells that survive after treatment and study them. There are drugs already approved or under development that inhibit macrophages in general or specifically CCL5 function.”